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1

Exploiting a natural conformational switch to engineer an interleukin-2 ‘superkine’

Levin, Aron M., Bates, Darren L., Ring, Aaron M., Krieg, Carsten, Lin, Jack T., Su, Leon, Moraga, Ignacio, Raeber, Miro E., Bowman, Gregory R., Novick, Paul, Pande, Vijay S., Fathman, C. Garrison, Boy

Journal:

Year:

2012

Language:

english

File:

PDF, 907 KB

english, 2012

2

The Association of MHC with Autoimmune Diseases: Understanding the Pathogenesis of Autoimmune Diabetes

William M. Ridgway, C.Garrison Fathman

Journal:

Clinical Immunology and Immunopathology

Year:

1998

Language:

english

File:

PDF, 119 KB

english, 1998

3

CD4-positive/heat-stable antigen-positive thymocytes cause graft-versus-host disease across non-major histocompatibility complex incompatibilities

Brett Charlton, Joseph Meltzer, C. Garrison Fathman

Journal:

European Journal of Immunology

Year:

1994

Language:

english

File:

PDF, 405 KB

english, 1994

4

Inhibition of immune induction: the target of current transplantation tolerance strategies

C Garrison Fathman

Journal:

Current Opinion in Immunology

Year:

1992

Language:

english

File:

PDF, 290 KB

english, 1992

5

Regulation of autoimmune response

William M. Ridgway, Howard L. Weiner, C.Garrison Fathman

Journal:

Current Opinion in Immunology

Year:

1994

Language:

english

File:

PDF, 1.36 MB

english, 1994

6

Gene therapy in autoimmune disease

Ingo H Tarner, C.Garrison Fathman

Journal:

Current Opinion in Immunology

Year:

2001

Language:

english

File:

PDF, 363 KB

english, 2001

7

MHC structure and autoimmune T cell repertoire development

William M Ridgway, C Garrison Fathman

Journal:

Current Opinion in Immunology

Year:

1999

Language:

english

File:

PDF, 78 KB

english, 1999

8

Th1 unresponsiveness can be infectious for unrelated antigens

CHARLTON, BRETT, FATHMAN, C GARRISON, SLATTERY, ROBYN M

Journal:

Immunology & Cell Biology

Year:

1998

Language:

english

File:

PDF, 318 KB

english, 1998

9

Functional similarities of AeEαIa molecules as determined by analysis with T-cell clones

Barbara N. Beck, Anthony J. Infante, C. Garrison Fathman

Journal:

Year:

1982

Language:

english

File:

PDF, 458 KB

english, 1982

10

I-Region genetic restrictions imposed upon the recognition of KLH by murine T-cell clones

Minoru Shigeta, C. Garrison Fathman

Journal:

Year:

1981

Language:

english

File:

PDF, 544 KB

english, 1981

11

Hybrid I region antigens and I region restriction of recognition in MLR

C. Garrison Fathman, P. Diane Infante

Journal:

Year:

1979

Language:

english

File:

PDF, 275 KB

english, 1979

12

Clones of alloreactive T cells

Hans Hengartner, C. Garrison Fathman

Journal:

Year:

1980

Language:

english

File:

PDF, 643 KB

english, 1980

13

DRB1*LY10— a newDRB1allele and its haplotypic association

Gregg R. McClure, Giovina Ruberti, C. Garrison Fathman, Henry A. Erlich, Ann B. Begovich

Journal:

Year:

1990

Language:

english

File:

PDF, 296 KB

english, 1990

14

A gene therapy approach to treatment of autoimmune disease

Christine M. Seroogy, C. Garrison Fathman

Journal:

Immunologic Research

Year:

1998

Language:

english

File:

PDF, 930 KB

english, 1998

15

An Analysis of Monoclonal T Cell and Antibody Recognition Sites on Ia Molecules.

Frelinger, John G., Shigeta, Minoru, Fathman, C. Garrison

Journal:

The Journal of Investigative Dermatology

Year:

1985

File:

PDF, 2.54 MB

1985

16

Clonal Growth of T Cells in vitro: Preliminary Attempts to a Quantitative Approach

Takeshi Watanabe, C. Garrison Fathman, Antonio Coutinho

Journal:

Immunological Reviews

Year:

1977

Language:

english

File:

PDF, 10.87 MB

english, 1977

17

Anti-CD4 Monoclonal Antibodies in Therapy: Creation of Nonclassical Tolerance in the Adult

Judith A. Shiztru, Susan E. Alters, C. Garrison Fathman

Journal:

Immunological Reviews

Year:

1992

Language:

english

File:

PDF, 8.47 MB

english, 1992

18

GRAIL: a unique mediator of CD4 T-lymphocyte unresponsiveness

Chan C. Whiting, Leon L. Su, Jack T. Lin, C. Garrison Fathman

Journal:

Year:

2011

Language:

english

File:

PDF, 751 KB

english, 2011

19

Induction of relapsing paralysis in experimental autoimmune encephalomyelitis by bacterial superantigen

Brocke, Stefan, Gaur, Amitabh, Piercy, Christopher, Gautam, Anand, Gijbels, Koenraad, Fathman, C. Garrison, Steinman, Lawrence

Journal:

Year:

1993

File:

PDF, 538 KB

1993

20

An array of possibilities for the study of autoimmunity

Fathman, C. Garrison, Soares, Luis, Chan, Steven M., Utz, Paul J.

Journal:

Year:

2005

Language:

english

File:

PDF, 588 KB

english, 2005

21

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes

Su, Leon, Sheng, Deqiao, Chang, Pearl, Atkinson, Mark, Czesak, Margaret, Yip, Linda, Albert, Paul R, Collier, Ai-Ris, Turley, Shannon J, Fathman, C Garrison

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 539 KB

english, 2009

22

CYLD: deubiquitination-induced TCR signaling

Fathman, C Garrison, Lineberry, Neil

Journal:

Nature Immunology

Year:

2006

Language:

english

File:

PDF, 358 KB

english, 2006

23

10.1038/ni0901-759

Ermann, Joerg, Fathman, C. Garrison

Journal:

Nature Immunology

Year:

2001

Language:

english

File:

PDF, 50 KB

english, 2001

24

Two isoforms of otubain 1 regulate T cell anergy via GRAIL

Soares, Luis, Seroogy, Christine, Skrenta, Heidi, Anandasabapathy, Niroshana, Lovelace, Patricia, Chung, Chan D, Engleman, Edgar, Fathman, C Garrison

Journal:

Nature Immunology

Year:

2003

Language:

english

File:

PDF, 4.24 MB

english, 2003

25

Protein microarrays for multiplex analysis of signal transduction pathways

Chan, Steven M, Ermann, Joerg, Su, Leon, Fathman, C Garrison, Utz, Paul J

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 1017 KB

english, 2004

26

CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation

Edinger, Matthias, Hoffmann, Petra, Ermann, Joerg, Drago, Kathryn, Fathman, C Garrison, Strober, Samuel, Negrin, Robert S

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 465 KB

english, 2003

27

Molecular mechanisms of CD4+ T-cell anergy

Fathman, C. Garrison, Lineberry, Neil B.

Journal:

Nature Reviews Immunology

Year:

2007

Language:

english

File:

PDF, 864 KB

english, 2007

28

Distinct B Cell Subpopulations Differ in Their Genetic Requirements for Activation by T Helper Cells

Alfred Singer, Yoshihiro Asano, Minoru Shigeta, Karen S. Hathcock, Aftab Ahmed, C. Garrison Fathman, Richard J. Hodes

Journal:

Immunological Reviews

Year:

1982

Language:

english

File:

PDF, 1.17 MB

english, 1982

29

Clonotypic Antibodies which Stimulate T Cell Clone Proliferation

John Frelinger, Amy Sing, Anthony Infante, C. Garrison Fathman

Journal:

Immunological Reviews

Year:

1984

Language:

english

File:

PDF, 5.48 MB

english, 1984

30

Treatment of Autoimmune Disease by Adoptive Cellular Gene Therapy

INGO H. TARNER, ANTHONY J. SLAVIN, JACQUELINE McBRIDE, ALENKA LEVICNIK, RICHARD SMITH, GARRY P. NOLAN, CHRISTOPHER H. CONTAG, C. GARRISON FATHMAN

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 166 KB

2003

31

T-cell anergy

Christine M. Seroogy, C. Garrison Fathman

Journal:

Immunologic Research

Year:

2003

Language:

english

File:

PDF, 100 KB

english, 2003

32

Peptides as therapy of autoimmune disease

C. Garrison Fathman

Journal:

Diabetes/Metabolism Research and Reviews

Year:

1993

Language:

english

File:

PDF, 589 KB

english, 1993

33

Stimulating the lymphocytes

C. Garrison Fathman

Journal:

Current Biology

Year:

1993

Language:

english

File:

PDF, 340 KB

english, 1993

34

GRAIL, an E3 ubiquitin ligase, is necessary for anergy induction in CD4+ T cells

L. Soares, C.M. Seroogy, C. Garrison Fathman

Journal:

Autoimmunity Reviews

Year:

2004

Language:

english

File:

PDF, 52 KB

english, 2004

35

Developing the concept of adoptive cellular gene therapy of rheumatoid arthritis

Ingo H. Tarner, Elena Neumann, Steffen Gay, C. Garrison Fathman, Ulf Müller-Ladner

Journal:

Autoimmunity Reviews

Year:

2006

Language:

english

File:

PDF, 226 KB

english, 2006

36

OR.78. Immature Dendritic Cells As Vehicles for Application in Adoptive Cellular Gene Therapy

Ulrich Purath, Elena Neumann, Remi Creusot, Shahriar Yaghoubi, Peter Haerle, Rainer Straub, C. Garrison Fathman, Ulf Mueller-Ladner, Ingo Tarner

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 40 KB

english, 2006

37

Targeted Cellular Gene Therapy Using IL-4 Secreting DCs Corrects Immune Dysregulations and Prevents Diabetes in NOD Mice

Remi J. Creusot, Shahriar Yaghoubi, Keiichi Kodama, Sam S. Gambhir, Demi Dang, C. Garrison Fathman

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 40 KB

english, 2007

38

Gene Expression Analysis by Microarray Following Anti-CD3 Antibody Therapy of NOD Mice

Hideyuki Iwai, Keichi Kodama, Demi Dang, C. Garrison Fathman, Jeffrey A. Bluestone

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 42 KB

english, 2007

39

Identification of Candidate IDDM Disease Susceptibility Genes in the Idd Regions of NOD Mice by Temporal Microarray Gene Expression Data Analysis

Keiichi Kodama, Demi Dang, Claire Holness, Hideyuki Iwai, Mark Hartnett, Atul Butte, C. Garrison Fathman

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 43 KB

english, 2007

40

Tissue-targeted therapy of autoimmune diabetes using dendritic cells transduced to express IL-4 in NOD mice

Rémi J. Creusot, Shahriar S. Yaghoubi, Keiichi Kodama, Demi N. Dang, Vu H. Dang, Karine Breckpot, Kris Thielemans, Sanjiv S. Gambhir, C. Garrison Fathman

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 1.24 MB

english, 2008

41

Tissue- and age-specific changes in gene expression during disease induction and progression in NOD mice

Keiichi Kodama, Atul J. Butte, Remi J. Creusot, Leon Su, Deqiao Sheng, Mark Hartnett, Hideyuki Iwai, Luis R. Soares, C. Garrison Fathman

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 637 KB

english, 2008

42

OR.85. Regulation of GRAIL Expression by mTOR Controls Naive CD4 T Cell Proliferation

Jack Lin, Neil Lineberry, Michael Kattah, Leon Su, Paul Utz, C. Garrison Fathman

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 52 KB

english, 2009

43

T.14. A Short Pulse of IL-4 Delivered Locally by mRNA Electroporated DCs is Sufficient to Prevent or Treat Autoimmune Diabetes in NOD Mice

Rémi Creusot, Pearl Chang, Shahriar Yaghoubi, Don Healey, Irina Tcherepanova, Charles Nicolette, C. Garrison Fathman

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 40 KB

english, 2009

44

F.86. Deaf1 Isoforms Control Changes in Peripheral Tissue Antigen Gene Expression in the Non-obese Diabetic Mouse Pancreatic Lymph Node during Type I Diabetes Pathogenesis

Linda Yip, Rémi Creusot, Deqiao Sheng, Pearl Chang, Margaret Czesak, Paul Albert, Ai-ris Collier, Shannon Turley, C. Garrison Fathman, Leon Su

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 39 KB

english, 2009

45

F.80. The TransmembraneE3 Ligase, GRAIL Ubiquitinates and Degrades CD83 on CD4+ T cells

Leon Su, Hideyuki Iwai, Jack Lin, C. Garrison Fathman

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 39 KB

english, 2009

46

F.124. CTLA-4 Ig Serves as a Surrogate for Tregs by Engaging Activation Induced CD80/86 on Murine T Effector Cells

Swati Acharya, C. Garrison Fathman

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 41 KB

english, 2009

47

Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis

Jack T. Lin, Emily A. Stein, Michael T. Wong, Krishna J. Kalpathy, Leon L. Su, Paul J. Utz, William H. Robinson, C. Garrison Fathman

Journal:

Clinical Immunology

Year:

2012

Language:

english

File:

PDF, 1.49 MB

english, 2012

48

High cell surface expression of CD4 allows distinction of CD4+CD25+ antigen-specific effector T cells from CD4+CD25+ regulatory T cells in murine experimental autoimmune encephalomyelitis

Jinzhu Li, William Ridgway, C. Garrison Fathman, Harley Y. Tse, Michael K. Shaw

Journal:

Journal of Neuroimmunology

Year:

2007

Language:

english

File:

PDF, 845 KB

english, 2007

49

Targeted gene therapy: frontiers in the development of ‘smart drugs’

Ingo H. Tarner, Ulf Müller–Ladner, C.Garrison Fathman

Journal:

Trends in Biotechnology

Year:

2004

Language:

english

File:

PDF, 155 KB

english, 2004

50

Bioluminescence imaging of lymphocyte trafficking in vivo

Jonathan Hardy, Matthias Edinger, Michael H Bachmann, Robert S Negrin, C.Garrison Fathman, Christopher H Contag

Journal:

Experimental Hematology

Year:

2001

Language:

english

File:

PDF, 206 KB

english, 2001